Microenvironment

   

  

Follicular lymphoma micro-environment

A great deal of study is being done on follicular lymphoma all the time. One area of intense study is the tumour microenvironment. This page brings you a list of studies on this fascinating topic.

 

The tumour microenvironment refers to the healthy, normal cells that surround and are inside the tumour. It is believed that perhaps it is these healthy cells that actually control the behaviour of the follicular lymphoma. Most studies tend to support this view, but others do not. We'll leave it up to you to decide.

 

Below are some of these studies to help you get started understanding this complex issue. But after you read those, you may wish to read the following report by Randy Gascoyne one of the worlds foremost haematopathologists, from the British Columbia Cancer Agency. He discusses how all this knowledge needs to be standardized so it can be used to plan patient treatments.

 

Gene expression signatures in follicular lymphoma: are they ready for the clinic?

 

Recently published articles (January 2009) which further define the microenvironment factors which predict for response to treatment. The first is the study, the second is an analysis of that studies findings by another expert.

 

Impact of the tumor microenvironment on prognosis in follicular lymphoma is dependent on specific treatment protocols

 

Clinicobiological, prognostic and therapeutic implications of the tumor microenvironment in follicular lymphoma
 

Following are some more studies regarding the microenvironment. The first one is quite technical, but fascinating. The rest are a bit less technical.