|
Follicular lymphoma micro-environment
A great deal of study is being done on follicular lymphoma all the time. One
area of intense study is the tumour microenvironment. This page brings you a
list of studies on this fascinating topic.
The tumour microenvironment refers to the healthy, normal cells that surround
and are inside the tumour. It is believed that perhaps it is these healthy cells
that actually control the behaviour of the follicular lymphoma. Most studies
tend to support this view, but others do not. We'll leave it up to you to
decide.
Below are some of these studies to help you get started understanding this
complex issue. But after you read those, you may wish to read the following
report by Randy Gascoyne one of the worlds foremost haematopathologists, from
the British Columbia Cancer Agency. He discusses how all this knowledge needs to
be standardized so it can be used to plan patient treatments.
Gene
expression signatures in follicular lymphoma: are they ready for the clinic?
Recently published articles (January 2009) which further define the
microenvironment factors which predict for response to treatment. The first is
the study, the second is an analysis of that studies findings by another expert.
Impact of the
tumor microenvironment on prognosis in follicular lymphoma is dependent on
specific treatment protocols
Clinicobiological, prognostic and therapeutic implications of the tumor
microenvironment in follicular lymphoma
Following are some more studies regarding the microenvironment. The first
one is quite technical, but fascinating. The rest are a bit less technical.
|