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Follicular microenvironment

A great deal of study is being done on follicular lymphoma all the time. One area of intense study is the tumour microenvironment. This page brings you a list of studies on this fascinating topic.

The tumour microenvironment refers to the healthy, normal cells that surround and are inside the tumour. It is believed that perhaps it is these healthy cells that actually control the behaviour of the follicular lymphoma. Most studies tend to support this view, but others do not. We'll leave it up to you to decide.

Below are some of these studies to help you get started understanding this complex issue.

• Prediction of survival in follicular lymphoma based on molecular features of tumor-infiltrating immune cells.

• High numbers of tumor-infiltrating FOXP3-positive regulatory T cells are associated with improved overall survival in follicular lymphoma

• Prognosis in Follicular Lymphoma — It's in the Microenvironment

• Survival signals within the tumour microenvironment suppress drug-induced apoptosis: lessons learned from B lymphomas

• The indispensable role of microenvironment in the natural history of low-grade B-cell neoplasms

• Human mesenchymal stem cells isolated from bone marrow and lymphoid organs support tumor B-cell growth: Role of stromal cells in follicular lymphoma pathogenesis

• High numbers of tumor-infiltrating FOXP3-positive regulatory T cells are associated with improved overall survival in follicular lymphoma

• Chronic B cell malignancies and bone marrow microenvironment

• Number of CD4+ cells and location of forkhead box protein P3-positive cells in diagnostic follicular lymphoma tissue microarrays correlates with outcome

• Absolute lymphocyte count predicts overall survival in follicular lymphomas

• Immunohistochemical Patterns of Reactive Microenvironment Are Associated With Clinicobiologic Behavior in Follicular Lymphoma Patients

• NCI Scientists Create Model That Predicts Follicular Lymphoma Survival

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